[HTML][HTML] RNA-Binding Macrocyclic Peptides
… of cyclic peptides that target more complex tertiary folds of … Structural studies of this new
RRM in complex with the TAR … structure of the peptide:RNA complex further revealed that the …
RRM in complex with the TAR … structure of the peptide:RNA complex further revealed that the …
[图书][B] Use of Lab-Evolved Proteins to Guide Development of Inhibitors that Target HIV-1 TAR RNA
SS Chavali - 2021 - search.proquest.com
… -Tat interaction represents a viable target for functional cure therapy. Numerous studies have
determined the structures of HIV TAR in complex with BIV-Tat … strong peptide–RNA binding …
determined the structures of HIV TAR in complex with BIV-Tat … strong peptide–RNA binding …
Correlation in Domain Fluctuations Navigates Target Search of a Viral Peptide along RNA
… peptide along with the solution NMR structure of the BIV TAR–Tat complex is shown in …
of the TAR RNA to generate the initial structure of the BIV TAR–Tat complex for simulations. …
of the TAR RNA to generate the initial structure of the BIV TAR–Tat complex for simulations. …
[HTML][HTML] Binding of hnRNP I–vRNA Regulates Sindbis Virus Structural Protein Expression to Promote Particle Infectivity
CE Westcott, S Qazi, AM Maiocco, S Mukhopadhyay… - Viruses, 2022 - mdpi.com
… The primary goal of this study was to determine whether the … RNA complexes in lysates
generated from HEK293 cells that … the native interaction site via the BIV-TAR/TAT system, we next …
generated from HEK293 cells that … the native interaction site via the BIV-TAR/TAT system, we next …
Genetically encoded RNA-based bioluminescence resonance energy transfer (BRET) sensors
L Mi, Q Yu, APKK Karunanayake Mudiyanselage… - ACS …, 2023 - ACS Publications
… In this project, our goal is to design a novel type of … wondered if natural RNA–protein
complexes can also be used to … Our results indicated that the fusion of Pepper and TAR via these …
complexes can also be used to … Our results indicated that the fusion of Pepper and TAR via these …
[PDF][PDF] Development of fluorogenic peptide probes carrying internally-incorporated cyanine dyes as FID indicators for dsRNAs
ETT Lee - tohoku.repo.nii.ac.jp
… small molecules that can specifically bind to RNA structural features … RNP complex– the
HIV-1 Tat protein – HIV-1 TAR RNA … with the drug target, as such, we have decided that a good …
HIV-1 Tat protein – HIV-1 TAR RNA … with the drug target, as such, we have decided that a good …
Crosslinked Helical Fork: Towards a Rationally Designed Encodable Scaffold for the Sequence-Specific Targeting of Double-Stranded RNA
JG Kwok - 2023 - search.proquest.com
… effort towards developing a scaffold that targets the stem duplex by … complexes, Rnt1p–siRNA20
and EIAV Tat–TAR,21 that have … While the native peptide-RNA complex features several …
and EIAV Tat–TAR,21 that have … While the native peptide-RNA complex features several …
Investigating chemical crosslinking of protein-RNA complexes by mass spectrometry
A Wulf - 2022 - ediss.uni-goettingen.de
… low-abundant crosslinked peptide-RNA moieties entering the mass … Crosslinking sites from
the NELF complex bound to TAR-… N-hydroxysuccinimide esters that specifically target primary …
the NELF complex bound to TAR-… N-hydroxysuccinimide esters that specifically target primary …
[PDF][PDF] Combating an intrinsic antibiotic resistance mechanism by interfering with small RNA regulation of an outer membrane porin
A Batresian - 2021 - scholarworks.calstate.edu
… TAR RNA complexes shows how two RNAs that are similar … The first goal of this study laid
the way for the subsequent goals … design rules for peptide-RNA interactions can be developed. …
the way for the subsequent goals … design rules for peptide-RNA interactions can be developed. …
Different views of the dynamic landscape covered by the 5'-hairpin of the 7SK small nuclear RNA
… in the formation of the complexes. The present manuscript thus … the buffer composition (pH
and Mg 2+ ) on the structure and … showing that Tat-ARM and HEXIM1-ARM peptides target …
and Mg 2+ ) on the structure and … showing that Tat-ARM and HEXIM1-ARM peptides target …